Aldosterone Excess, Hypertension, and Chromosome 7p22

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Aldosterone excess, hypertension, and chromosome 7p22: evidence continues to mount.

In recent years, numerous groups of investigators have reported primary aldosteronism (PAL) to be much more common than previously thought.1–4 This has followed recognition of the aldosterone/renin ratio (ARR) as an improved, more sensitive method of screening for PAL and the application of ARR testing to a wider population, to include normokalemic, as well as hypokalemic, hypertensive subjects...

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Essential hypertension and aldosterone.

MANY FACTORS have been implicated in the etiology of essential hypertension and at present the primary cause of this disease remains obscure. The relationship of sodium to the development of hypertension and the question of involvement of the adrenal cortex has been the subject of numerous investigations. Efforts by earlier investigators to show a hypersecretion of corticosteroids in this condi...

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Urinary aldosterone and hypertension.

A POSSIBLE ETIOLOGIC ROLE of the 18.1kadrenal cortex in the genesis of clinical hypertension has been recognized since Goldblatt's demonstration in 1937 that adrenalectomy prevents the expected development of hypertension following bilateral renal artery constriction.' Recently, interest in this possibility has been intensified by reports that some hypertensive patients excrete2-6 and secrete7 ...

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Role of angiotensinogen and relative aldosterone excess in salt-sensitive hypertension.

Role of Angiotensinogen and Relative Aldosterone Excess in Salt-Sensitive Hypertension To the Editor: We read with great interest the article by Michel et al. They demonstrated that circulating angiotensinogen concentration (AGT) was positively associated with aldosterone level and blood pressure in subjects of African ancestry with high urinary Na/K ratio. Their findings may elucidate one of t...

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Association of aldosterone excess and apnea-hypopnea index in patients with resistant hypertension

The present study was to investigate the association of aldosterone excess and apnea-hypopnea index (AHI) in patients with resistant hypertension. Patients with resistant hypertension were enrolled and baseline characteristics including plasma aldosterone concentration (PAC) and 24 h-urine aldosterone levels were collected and compared between groups with different degrees of AHI as assessed by...

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ژورنال

عنوان ژورنال: Hypertension

سال: 2007

ISSN: 0194-911X,1524-4563

DOI: 10.1161/01.hyp.0000260141.30703.0c